Patient zero : a curious history of the world's worst diseases / Lydia Kang, MD, Nate Pedersen.
Book | Workman Publishing | 2021

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x, 390 pages : illustrations (chiefly color) ; 22 cm.
Includes bibliographical references (pages 358-376) and index.
Introduction -- Infection -- Patient zero: ergotism -- Zoonoses: making the leap -- Patient zero: ebola -- Germ theory: from miasma to microscopes -- Patient zero: the plague -- Autopsy: from humoral theory to grave robbing -- Patient zero: mad cow disease -- Anatomy of an outbreak: calling in the public health cavalry -- Patient zero: yellow fever -- Covid-19: the origins of SARS-CoV-2 and the politicization of plagues -- Spread -- Patient zero: HIV -- Indigneous peoples & the Columbian exchange: the "exchange" was not equal -- Patient zero: typhus -- Patient zero: measles -- Patient zero: Hansen's disease (leprosy) -- Patient zero: syphilis -- Quackery: from mercury and bloodletting to hydroxychloroquine -- Patient zero: typhoid fever -- Containment -- Patient zero: 1918 influenza -- Vaccines: from variolation to messenger RNA -- Patient zero: polio -- Patient zero: hepatitis C -- The infection-disease link: from viruses, bacteria, and parasites to cancer -- Patient zero: cholera -- Anthrax & biological warfare: the weaponization of disease -- Patient zero: rabies -- Tuberculosis: the "all-consuming" disease -- Patient anti-zero: the last smallpox case -- Medical advances: from pandemics to progress.
"From the masters of storytelling-meets-science and co-authors of Quackery, Patient Zero tells the long and fascinating history of disease outbreaks-how they start, how they spread, the science that lets us understand them, and how we race to destroy them before they destroy us. Written in the authors' lively and accessible style, chapters include page-turning medical stories about a particular disease or virus-smallpox, Bubonic plague, polio, HIV-that combine "Patient Zero" narratives, or the human stories behind outbreaks, with historical examinations of missteps, milestones, scientific theories, and more. Learn the tragic stories of Patient Zeros throughout history, such as Mabalo Lokela, who contracted Ebola while on vacation in 1976, and the Lewis Baby on London's Broad Street, the first to catch cholera in an 1854 outbreak that led to a major medical breakthrough. Interspersed are origin stories of a different sort-how a rye fungus in 1951 turned a small village in France into a phantasmagoric scene reminiscent of Burning Man. Plus the uneasy history of human autopsy, how the HIV virus has been with us for at least a century, and more"-- Provided by publisher.
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